Increase in HO-1 transcripts and decrease in 8-isoprostane concentration in monocyte-derived macrophages from control participants. Real-time quantitative PCR, with raw data normalised to GAPDH, indicated increased HO-1 expression levels in DHA-supplemented non-stimulated macrophages and a trend for increase in LPS-stimulated macrophages exposed to DHA (A). In parallel, significant decreases were observed in 8-isoprostane concentrations in supernatants from hemin- and LPS-stimulated macrophages (B). Values are mean ± SEM of duplicate determinations (n = 5). *p < 0.05.