Figure 5 | Scientific Reports

Figure 5

From: Structural features in the glycine-binding sites of the GluN1 and GluN3A subunits regulate the surface delivery of NMDA receptors

Figure 5

The glycine-binding sites in the GluN1 and GluN3A subunits regulate the surface expression of NMDARs in hippocampal neurones. (a,c) Representative images of cultured rat hippocampal neurones transfected at DIV10 with the indicated YFP-GluN1-1a (a) or GFP-GluN3A (c) subunits; at DIV14, surface and total subunits were stained using an anti-GFP antibody. (b,d) Summary of the relative surface expression of the indicated subunits measured in 10-µm segments of secondary or tertiary dendrites (n ≥ 30 segments in ≥ 6 different cells per group); *p < 0.05 vs. GluN1-1a (b) or GluN3A (d) (ANOVA).

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