Modulation of p43 signaling affects early muscle fibrosis. (A,C) Sirius Red staining on cryosections of regenerated Tibialis muscles in wild-type, p43−/− and p43-Tg mice at 28 d.p.i and 70.d.p.i. (B,D) Quantification of Sirius Red staining (H) muscles in wild-type, p43−/− and p43-Tg mice at 28 d.p.i. and 70.d.p.i. (n = 6 for each group). Statistical significance: *p < 0.05; **p < 0.01; ***p < 0.001. Student’s t-test. Results are expressed as ± sem.