Table 2 Short-term (10 years) cost-effectiveness analysis for lifestyle interventions among individuals with prediabetes.

From: Comparing the Lifestyle Interventions for Prediabetes: An Integrated Microsimulation and Population Simulation Model

  Intervention Type
DPP DPP-YMCA HELP-PD
Age group   55–65 yrs  
Diabetes averted (1000 s) 258.78 150.35 226.00
Death averted (1000 s) 18.24 4.96 22.80
Gain in diabetes-free survival time (Years) 0.03 0.02 0.03
Intervention cost ($1000) 31,074,700 7,677,100 10,039,300
Aversion savings ($1000) 22,048,056 12,809,820 19,255,200
Total savings ($1000) −9,026,644 5,132,720 9,215,900
Age group   45–65 yrs  
Diabetes averted (1000 s) 489.06 296.67 509.60
Death averted (1000 s) 44.08 26.35 58.00
Gain in diabetes-free survival time (Years) 0.06 0.03 0.06
Intervention cost ($1000) 62,174,800 15,361,400 20,088,000
Aversion savings ($1000) 41,667,912 25,276,284 43,417,920
Total savings ($1000) −20,506,888 9,914,884 23,329,920
Age group   35–65 yrs  
Diabetes averted (1000 s) 652.84 394.32 764.00
Death averted (1000 s) 77.14 44.95 107.60
Gain in diabetes-free survival time (Years) 0.07 0.05 0.08
Intervention cost ($1000) 92,405,900 22,829,300 29,853,700
Aversion savings ($1000) 55,621,968 33,596,064 65,092,800
Total savings ($1000) −36,783,932 10,766,764 35,239,100
Age group   25–65 yrs  
Diabetes averted (1000 s) 915.80 553.35 927.60
Death averted (1000 s) 83.98 62.31 130.40
Gain in diabetes-free survival time (Years) 0.11 0.06 0.11
Intervention cost ($1000) 126,929,900 31,358,600 41,007,400
Aversion savings ($1000) 78,026,160 47,145,420 79,031,520
Total savings ($1000) −48,903,740 15,786,820 38,024,120