Peak intensity of Aβ(1–40) and Aβ(1–42) following titration with STAB-MAb. Histograms (A,B) represent the residue-specific normalized intensity (in arbitrary units) of 15N isotopically labeled Aβ(1–40) and Aβ(1–42) in the absence and presence of 1:3 ratio of labeled peptide to unlabeled STAB-MAb. Black bars represent the standard error (SE) determined based on the signal to noise ratio. Overlapping the histogram is a color-coded representation of the different secondary structures identified within the Aβ(1–40) peptide in 93% H2O/7% D2O (PDB ID. 2LFM) and for Aβ(1–42) in 70% H2O/30% hexafluoroisopropanol-D2O (PDB ID. 1Z0Q)9,15.