Figure 1 | Scientific Reports

Figure 1

From: Exploring Notch Pathway to Elucidate Phenotypic Plasticity and Intra-tumor Heterogeneity in Gliomas

Figure 1

Activity Ratio (AR) scores of the input molecules of (A) aNSC (B) GSC and (C) GBM Model simulations. The AR-scores of each input molecules were calculated for every cellular state. TP53 protein was found as mutated in the “GSC Model” simulation. On the other hand, while simulating “GBM Model”, TP53 protein was found mutated along with increased activities of RBPJ+/+, JAK2+/+ and STAT3+/+ proteins.

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