Figure 8 | Scientific Reports

Figure 8

From: First crystal structure of an endo-levanase – the BT1760 from a human gut commensal Bacteroides thetaiotaomicron

Figure 8

A model of initial events of levan utilization by B. thetaiotaomicron. (a) Genomic arrangement of levan utilization locus (the fructan PUL). (b) A proposed schematic model of levan binding, hydrolysis and transport of hydrolysis products into the periplasm. The SusE-like membrane anchored BT17613 is suggested to mediate levan binding, while the endo-levanase (BT1760) cleaves the fructan polymer into fructo-oligosaccharides (L-FOS). The L-FOS are transported into the periplasm via SusC- and SusD-like complex of BT1762 and BT1763 proteins (PDB: 5T3R;36).

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