Table 1 Regulation of MyoG promoter by mDia1 mutant-Phb2 interaction.

From: Cytoplasmic sequestration of the RhoA effector mDiaphanous1 by Prohibitin2 promotes muscle differentiation

Expressed proteins FH2 motif MyoG promoter Proposed mechanism of action
mDia1ΔN3 Present Repressed FH2 motif-mediated repression
mDia1H + P Absent No effect No FH2 motif-mediated repression
mDia1ΔN3(HindIII) Absent No effect No FH2 motif-mediated repression
mDia1CC Absent No effect No FH2 motif-mediated repression
Phb2 Not applicable No effect No effect
mDia1ΔN3 + Phb2 Present in mDia1 mutant Rescued Phb2 recruits pro-myogenic proteins to FH2 motif