Table 1 Demographic characteristics of the participants.

From: Gray Matter Alterations in Early and Late Relapsing-Remitting Multiple Sclerosis Evaluated with Synthetic Quantitative Magnetic Resonance Imaging

  HC Early RRMS Late RRMS p-value Post-hoc
HC vs. Early HC vs. Late Early vs. Late
Number 15 14 28     
Age, mean (SD) (years)* 41.07 (9.19) 36.07 (8.27) 41.18 (7.66) 0.20    
Sex (male/female) 2/13 6/8 4/24 0.07    
Disease duration, mean (SD) (years) NA 3.29 (1.54) 12.14 (6.59) 0.00002    
EDSS score, median (range) NA 0.5 (0–2.5) 1 (0–6.5) 0.30    
GM-MyVol, mean (SD) (mL) 23.67 (4.12) 22.90 (2.37) 19.80 (2.96) 0.0006 0.90 0.002 0.002
Whole GM-Vol, mean (SD) (mL) 694.71 (48.03) 725.48 (78.54) 675.44 (53.78) 0.10    
  1. GM-Vol, gray matter volume; GM-MyVol, myelin volume of gray matter; HC, healthy control; NA, not applicable; RRMS, relapsing-remitting multiple sclerosis; SD, standard deviation. Note: the statistical analyses were performed with one-way ANOVA*, χ2 test, non-parametric Kruskal Wallis, and Mann-Whitney U test.