Table 3 Hazard Ratio for the Association between Rotavirus Vaccination and Type 1 Diabetes, 2006–2017.

From: Lower Incidence Rate of Type 1 Diabetes after Receipt of the Rotavirus Vaccine in the United States, 2001–2017

  Unadjusted Hazard Ratio 95% CI p value Adjusted Hazard Ratio 95% CI p value
Vaccination
   Completed Rotavirus Series 0.64 0.52, 0.79 <0.001 0.67 0.54, 0.83 <0.001
   Not vaccinated     1.00 (reference)  
Sex
   Girls     1.04 0.84, 1.28 0.734
   Boys     1.00 (reference)  
Season of Birth
   Spring     1.55 1.12, 2.14 0.008
   Summer     1.36 0.98, 1.90 0.068
   Autumn     1.42 1.02, 1.97 0.039
   Winter     1.00 (reference)  
Residence at Birth
   New England, New Jersey     1.00 (reference)  
   New York, Pennsylvania     0.84 0.49, 1.44 0.533
   Middle Atlantic     0.78 0.49, 1.26 0.315
   Southeast     0.64 0.41, 1.00 0.051
   Michigan, Indiana, Ohio, Kentucky     0.81 0.50, 1.32 0.399
   North Central     0.55 0.33, 0.92 0.023
   Middle Central     0.58 0.34, 0.99 0.047
   South Central     0.51 0.32, 0.82 0.005
   Mountain     0.90 0.57, 1.42 0.640
   Pacific     0.87 0.56, 1.35 0.542