Figure 2 | Scientific Reports

Figure 2

From: A 3D bioprinter platform for mechanistic analysis of tumoroids and chimeric mammary organoids

Figure 2

Bioprinted tumoroids maintain expected cytokeratin expression and high percentage of proliferative cells. (a,b) MCF-7 tumoroids stained negative for CK-5 (green) and positive for CK-8 (red). B) MDA-MB-468 tumoroids stained positive for both CK-5 (green) and CK-8 (red). (c,d) Ki67 staining of MCF-7 (c) and MDA-MB-468 (d) tumoroids. (e) Quantitation of ki67+ MCF-7 and MDA-MB-468 cells compared to MCF-12A cells. *p < 0.05; **p < 0.01. (Scale bars: a and b = 50 µm, c and = 100 µm).

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