Figure 5 | Scientific Reports

Figure 5

From: Mitochondrial Oxidative Phosphorylation defect in the Heart of Subjects with Coronary Artery Disease

Figure 5

Supercomplexes activity and formation in human hearts. (A) Supercomplex I (Respirasome) formation (n = 4 in each group) (B) Supercomplex II (Synthatosome) formation (n = 4 in each group), (C) Complex I NDUFAB1 subunit expression (n = 4 in each group), (D) NADH Oxidase Activity (n = 8 in each group), (E) NADH-ubiquinone dehydrogenase activity (n = 8 in each group), (F) NADH-cytochrome c oxidoreductase, (G) NADH-ubiquinone dehydrogenase activity in the presence and absence of N-ethylmaleimide (NEM), (n = 8 in each group), Values are expressed as mean ± SEM in arbitrary unit (AU); *p < 0.05 t student test vs Non-CAD heart extracts.

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