Figure 12 | Scientific Reports

Figure 12

From: Enhancement of HIFU ablation by sonosensitizer-loading liquid fluorocarbon nanoparticles with pre-targeting in a mouse model

Figure 12

Apoptosis in tumors for different groups. TUNEL detection was performed to assess the apoptosis in tumors. (A) HIFU. (B) PLGA+HIFU. (C) PFP/PLGA+HIFU. (D) HMME/PLGA+HIFU. (E) HMME+PFP/PLGA+HIFU. (F) HMME+PFP/PLGA-Ab+HIFU. (G) HMME+PFP/PLGA-SA+HIFU. The TUNEL staining showed that brown staining with different degrees in the nucleus for each group. The cells with the strongest staining were noted for the pre-targeting (HMME+PFP/PLGA-SA+HIFU) group, followed by the direct targeting (HMME+PFP/PLGA-Ab+HIFU) group. The cells with the weakest staining were observed in the HIFU group.

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