Table 1 Automatically assessed model parameters for experimental datasets given in Fig. 4.

From: Quantitative dynamics of reversible platelet aggregation: mathematical modelling and experiments

Parameter 2.5 µM ADP 5 µM ADP 10 µM ADP 20 µM ADP 2.5 µM ADP 5 µM ADP 10 µM ADP 20 µM ADP 40 µM ADP
single single single single dual dual dual dual dual
probability of a platelet attachment to an existing aggregate, k1, 1/([plt]*s) 8.6*10−4 6.8*10−4 5.2*10−4 4.3*10−4 4.8*10−6 4.6*10−6 1.3*10−5 1.8*10−5 1*10−5
probability of single platelet detachment from an aggregate, k−1, 1/s 1.0*10−9 4.0*10−16 3.5*10−15 1.0*10−4 3.2 1.22 1.15 0.39 0.2
probability of one aggregate formation from two existing, k−2, 1/([plt]*s) 6.7*10−4 3.8*10−4 2.3*10−4 7.6*10−7 5.7*10−7 2.5*10−7 8.7*10−8 7.1*10−8 6.5*10−8
probability of an aggregate fragmenting into two, k3, 1/s 0.07 0.03 0.02 0.005 0.03 0.017 0.009 0.007 0.0035
probability of a new aggregate formation, k2, 1/([plt]*s) 3.8*10−5 3.9*10−5 5.1*10−5 2.7*10−4 2.5*10−10 1.0*10−9 2.5*10−9 1.7*10−8 3*10−8
initial concentration of platelets, p0, [plt] 100 100 100 100 742779 433994 125561 54038 35000