Table 2 ROC analysis for the pair comparisons.

From: Different Circulating Trace Amine Profiles in De Novo and Treated Parkinson’s Disease Patients

Variable Type AUC CI AUC (95%) Power Specificity Sensitivity
DN vs. H
TYRA DN > H 0.902 0.784–1.000 0.998 0.90 0.86
β-PEA H > DN 0.719 0.484–0.953 0.528 0.60 0.90
OCT H > DN 0.586 0.350–0.820 0.119 0.50 0.76
TRY DN > H 0.752 0.575–0.929 0.663 0.80 0.76
SYN H > DN 0.648 0.418–0.876 0.270 0.60 0.81
NE H > DN 0.476 0.263–0.689 0.041 0.50 0.62
5-HT H > DN 0.548 0.333–0.761 0.064 0.70 0.52
E DN > H 0.519 0.306–0.731 0.037 0.50 0.57
MTN DN > H 0.669 0.479–0.858 0.339 1.00 0.52
ADE DN > H 0.486 0.281–0.690 0.034 0.80 0.38
GABA DN > H 0.619 0.410–0.828 0.190 0.80 0.48
TYRO H > DN 0.557 0.342–0.772 0.075 0.70 0.48
TRP H > DN 0.690 0.501–0.879 0.417 0.90 0.57
DN vs. PD
TYRA PD > DN 0.825 0.702–0.948 0.993 0.76 0.78
β-PEA DN > PD 0.566 0.391–0.740 0.124 0.71 0.63
OCT PD > DN 0.516 0.346–0.685 0.039 0.57 0.67
TRY DN > PD 0.644 0.480–0.806 0.417 0.76 0.63
SYN PD > DN 0.697 0.537–0.856 0.679 0.86 0.63
NE DN > PD 0.757 0.612–0.900 0.902 0.67 0.89
5-HT DN > PD 0.688 0.525–0.849 0.636 0.71 0.70
E DN > PD 0.594 0.429–0.759 0.207 0.71 0.56
MTN PD > DN 0.641 0.474–0.807 0.404 0.48 0.81
ADE PD > DN 0.504 0.336–0.672 0.028 0.57 0.48
GABA DN > PD 0.563 0.397–0.728 0.115 0.57 0.59
TYRO PD > DN 0.775 0.640–0.910 0.943 0.71 0.78
TRP PD > DN 0.674 0.513–0.833 0.567 0.67 0.78
  1. In the column Type the symbol “>” is used to indicate that the metabolite concentrations of the group on the left of the symbol is greater than that of the group on the right; AUC = area under the curve; CI AUC (95%) = confidence interval of the Area Under the ROC curve at the level of 95%; power = post hoc power of ROC analysis given α = 0.05; specificity and sensitivity correspond to the closest top left point of the ROC curve.