Figure 8 | Scientific Reports

Figure 8

From: The secreted Ly6/uPAR-related protein-1 suppresses neutrophil binding, chemotaxis, and transmigration through human umbilical vein endothelial cells

Figure 8

Schematic summary of the effects of SLURP1 on neutrophil-endothelial interaction. Data presented in this report demonstrate that SLURP1 acts as an immunomodulatory protein by stabilizing the endothelial barrier function (green arrows), and by suppressing neutrophil (i) binding to endothelial cell surface, (ii) transmigration, (iii) polarization and (iv) chemotaxis (red blunt-ended lines).