Figure 6 | Scientific Reports

Figure 6

From: The secreted Ly6/uPAR-related protein-1 suppresses neutrophil binding, chemotaxis, and transmigration through human umbilical vein endothelial cells

Figure 6

SLURP1 suppresses MMP9 expression and activity. (A) QPCR evaluation of MMP9 transcript levels in TNF-α-activated dHL-60 cells in the presence or absence of SLURP1. (B) Representative zymogram showing MMP9 activity in cell culture supernatants under different conditions tested. Relative MMP9 activity under these conditions, quantified by densitometry is shown on the right. The data presented is an average of three independent experiments, each with a minimum of two replicates. CP, control protein mock purified from the parental strain lacking SLURP1 expression vector.