Figure 1 | Scientific Reports

Figure 1

From: The secreted Ly6/uPAR-related protein-1 suppresses neutrophil binding, chemotaxis, and transmigration through human umbilical vein endothelial cells

Figure 1

SLURP1 suppresses the interaction of TNF-α-activated dHL-60 and primary human neutrophils with TNF-α-activated HUVEC monolayer. The number of unstimulated or TNF-α-activated (A) dHL-60 cells and (B) primary human neutrophils bound to a confluent HUVEC monolayer upon treatment with control protein (CP; mock purified control protein from the parental strain without SLURP1 expression vector) or SLURP1 is shown. An unpaired t test was used to compare means of CP + TNF-α and SLURP1 + TNF-α and p value is shown in the graph. The data presented is representative of three independent experiments, each with a minimum of four replicates.

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