Figure 3 | Scientific Reports

Figure 3

From: microRNA-155 inhibition restores Fibroblast Growth Factor 7 expression in diabetic skin and decreases wound inflammation

Figure 3

Diabetes significantly increases the expression of proteins involved in miR processing. Expression of Drosha2 (A), DiGeorge Syndrome Chromosomal Region 8 (DGCR8) (B), TAR RNA Binding Protein 1 (TRBP-1) (C) and Dicer (D) in skin wound samples from control and diabetic mice (n = 6 for each group), collected at baseline (day 0) and at days 3 and 10 post wounding. mRNA levels were quantified by q-RT-PCR and normalized to the mean of TFIIB and U6 levels and control baseline. Data were analyzed by two-way ANOVA with Dunnet’s post hoc correction; *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.