Figure 1 | Scientific Reports

Figure 1

From: microRNA-155 inhibition restores Fibroblast Growth Factor 7 expression in diabetic skin and decreases wound inflammation

Figure 1

Diabetes significantly alters miR expression pattern and delays wound healing. (A) Wound size was assessed as percentage of initial size, along 10 days, in control and diabetic mice (n = 6 for each group). (B) Expression of 641 unique miRs, shown as heat map, in skin wound samples from the same control and diabetic mice, collected at baseline (day 0) and at days 3 and 10 post wounding. miR expression levels were normalized to the levels of U6 present on the arrays and control levels at day 0. MiRs changed by more than 2-fold (up or down) were included in the heat map. Data were analyzed using Student’s t-test; *p < 0.05; **p < 0.01; ***p < 0.001.