eBrain tissue uptake simulation. (A) Axial plane perspective under differed uptakes and doses parameters. Uptake levels are colored from low (blue) to high (red). Sampling points at time 1.0 simulated hour, dose: 1e3, 10e3 and 1000e3 simulated Molar and tissue uptake of 2e−3 20e−3 and 200e−3 simulated absorption units. See also Supplementary Clip 3. (B) Comparison of the simulation with FDG-PET brain CT. Elderly adult whose glucose uptake is normal (Top) and Alzheimer’s disease patient whose glucose uptake is reduced (Bottom). The FDG-PET brain CT images in Subfigure B are not covered by the CC BY license. Image credit to Berti et al.30 and S. Karger AG, Basel. All rights reserved, used with permission.