Figure 7 | Scientific Reports

Figure 7

From: The pro-angiogenic role of hypoxia inducible factor stabilizer FG-4592 and its application in an in vivo tissue engineering chamber model

Figure 7

Representative images and morphometric analysis of CD31 immunohistochemical (IHC) staining sections. Morphometric analysis (B,C,D) performed based on CD31 staining images (A). Although the amount of neovasculature in the HD group was lower than in NC group (B), the neovasculature of HD group had a larger average vessel area (C). Furthermore, FG-4592 reduced vessel shape index in a dose-dependent manner, suggesting that neovasculature tended to grow upwards after drug treatment (D). *p < 0.05, **p < 0.01, ***p < 0.001. Scale bar = 100 um.