Figure 10 | Scientific Reports

Figure 10

From: The pro-angiogenic role of hypoxia inducible factor stabilizer FG-4592 and its application in an in vivo tissue engineering chamber model

Figure 10

Locally administered FG-4592 does not promote inflammation or exert systemic effects. To examine inflammatory response, fibrovascular tissue at the matrix-host interface was selected as the region of interest (A). There were no significant differences in terms of MAC2 (+) cell numbers among the three groups (B). To examine the systemic effect, rat kidneys were used to perform HIF-1α staining (A) and no significant differences in terms of HIF-1α (+) cell numbers were found among the groups (C). Scale bar: black = 100 um, blue = 25 um.