Table 3 Multivariate Cox hazard regression for risk factors of OS and PFS in Patients with ARL.

From: The clinical features and prognosis of 100 AIDS-related lymphoma cases

VariablesHazard ratio (95% CI)
OSP valuePFSP value
Age
<45 yearsReference Reference 
≥45 years0.45 (0.20–0.97)0.0431.12 (0.56–2.24)0.740
Sex
MaleReference Reference 
Female1.49 (0.74–3.00)0.2691.10 (0.61–1.97)0.752
Baseline CD4 count
<100 cells/mm3Reference Reference 
≥100 cells/mm30.52 (0.27–1.02)0.0560.57 (0.31–1.04)0.067
Treatment
Non-chemotherapyReference Reference 
Chemotherapy0.16 (0.06–0.39)<0.0010.24 (0.09–0.62)0.003
Age-adjusted IPI
1–2Reference Reference 
3–411.92 (2.76–51.52)0.0012.14 (0.78–5.89)0.140
Ann Arbor stage
I–IIReference Reference 
III–IV2.00 (0.99–4.06)0.0541.53 (0.80–2.93)0.201
LDH
Normal LDHReference Reference 
Elevated LDH2.32 (1.09–4.92)0.0291.46 (0.81–2.62)0.208
Site
IntranodalReference Reference 
Extranodal1.47 (0.80–2.71)0.2141.09 (0.65–1.82)0.743
Histology
Diffuse large B-cellReference Reference 
Burkitt/Burkitt-like5.94 (2.49–14.17)<0.0012.68 (1.20–6.00)0.016
Other non-Hodgkin’s lymphoma0.55 (0.25–1.22)0.1410.62 (0.29–1.34)0.222
Hodgkin’s lymphoma0.000.9741.04 (0.34–3.25)0.940
  1. IPI, International Prognostic Index; LDH, lactate dehydrogenase; PFS, progression-free survival; OS, overall survival.