Figure 1 | Scientific Reports

Figure 1

From: Functional detection of botulinum neurotoxin serotypes A to F by monoclonal neoepitope-specific antibodies and suspension array technology

Figure 1

Cleavage sites of BoNT serotypes pathogenic to humans or animals in SNAP-25 or VAMP-2. Serotypes can be distinguished by their substrate specificity and specific cleavage position. After cleavage, neo-epitopes arise on both the C- and N-terminal ends of the cleavage sites that can be detected by highly specific neo-epitope antibodies.

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