In vitro insulin infusion profiles of the WIIDS. (A) The MDP could infuse insulin with the WIIDS in a highly reproducible manner. The infused amounts of insulin were 0.509 ± 0.008 U and 0.948 ± 0.019 U with one and two consecutive actuations, respectively. The error bars are the s.d. (B) Insulin infusion could be restricted depending on the pre-set criteria of the safety features: (a) Error 1, due to a disrupted minimum infusion interval; (b) Error 2, due to an exceeded maximum infusion dosage; and (c) Error 3, due to an exceeded daily maximum dosage. The error bars are the s.d.