Figure 5 | Scientific Reports

Figure 5

From: Prenatal Allergen Exposure Perturbs Sexual Differentiation and Programs Lifelong Changes in Adult Social and Sexual Behavior

Figure 5

Effects of prenatal allergic challenge on male-typical reproductive behaviors in adulthood. Adult females exposed to a maternal allergic challenge in utero began mounting more quickly (A) and mounted more frequently (B) than control females such that they were indistinguishable from control males. (C) In olfactory preference testing, males showed a significant bias in odor preference compared to female counterparts; however, odor preference was abolished in males experiencing allergic challenge in utero relative to unchallenged males. Allergic challenge in utero had no significant effect on odor preference of female littermates (p = 0.2). Data presented as mean + SEM. *Indicates p < 0.05. Group sizes: A-B: ♂V n = 6, ♂OVA n = 9, ♀V n = 5, Ova ♀ n = 9. C: ♂V n = 7, ♂Ova n = 7, ♀V n = 6, Ova ♀ n = 7.

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