Table 3 Treatments effects in Dp(16)1Yey hippocampus.

From: Prenatal treatment with EGCG enriched green tea extract rescues GAD67 related developmental and cognitive defects in Down syndrome mouse models

Density   T1 T2
F P value F P value
GAD67 neurons density/Neun Interaction F (1, 15) = 13,05 P = 0,0026 F (1, 15) = 10,20 P = 0,0061
genotype F (1, 15) = 14,71 P = 0,0016 F (1, 15) = 4,737 P = 0,0459
Treatment F (1, 15) = 2,906 P = 0,1088 F (1, 15) = 5,197 P = 0,0377
Protein levels
GAD67 Interaction F (1, 36) = 6,463 P = 0,0155 F (1, 39) = 5,009 P = 0,0310
genotype F (1, 36) = 2,524 P = 0,1209 F (1, 39) = 8,170 P = 0,0068
Treatment F (1, 36) = 3,264 P = 0,0792 F (1, 39) = 8,384 P = 0,0062
GAD65 Interaction F (1, 36) = 5,339 P = 0,0267 F (1, 36) = 6,773 P = 0,0134
genotype F (1, 36) = 1,336 P = 0,2554 F (1, 36) = 2,270 P = 0,1406
Treatment F (1, 36) = 3,707 P = 0,0621 F (1, 36) = 6,133 P = 0,0181
VGAT1 Interaction F (1, 35) = 0,6496 P = 0,4257 F (1, 38) = 6,439 P = 0,0154
genotype F (1, 35) = 16,96 P = 0,0002 F (1, 38) = 11,55 P = 0,0016
Treatment F (1, 35) = 11,48 P = 0,0018 F (1, 38) = 17,73 P = 0,0002
GLUR2 Interaction F (1, 38) = 2,348 P = 0,1338 F (1, 38) = 9,081 P = 0,0046
genotype F (1, 38) = 0,8522 P = 0,3618 F (1, 38) = 0,2135 P = 0,6467
Treatment F (1, 38) = 4,214 P = 0,0470 F (1, 38) = 4,355 P = 0,0437
VGLUT1 Interaction F (1, 33) = 5,490 P = 0,0253 F (1, 34) = 10,12 P = 0,0031
genotype F (1, 33) = 0,4361 P = 0,5136 F (1, 34) = 2,353 P = 0,1343
Treatment F (1, 33) = 0,2981 P = 0,5888 F (1, 34) = 24,94 P < 0,0001
VGAT1/VGLUT Interaction F (1, 33) = 31,04 P < 0,0001 F (1, 33) = 42,19 P < 0,0001
genotype F (1, 33) = 27,94 P < 0,0001 F (1, 33) = 33,47 P < 0,0001
Treatment F (1, 33) = 34,99 P < 0,0001 F (1, 33) = 4,400 P = 0,0437