Table 1 Treatments effects in mBACtgDyrk1a hippocampus.

From: Prenatal treatment with EGCG enriched green tea extract rescues GAD67 related developmental and cognitive defects in Down syndrome mouse models

Density   T1 T2 T3
F P value F P value F P value
GAD67 neurons density/Neun Interaction F (1, 14) = 12,76 P = 0,0031 F (1, 14) = 18,74 P = 0,0007 F (1, 14) = 0,6947 P = 0,4186
Genotype F (1, 14) = 14,85 P = 0,0018 F (1, 14) = 11,31 P = 0,0046 F (1, 14) = 44,62 P < 0,0001
Treatment F (1, 14) = 55,17 P < 0,0001 F (1, 14) = 21,88 P = 0,0004 F (1, 14) = 0,9450 P = 0,3475
Protein levels
GAD67 Interaction F (1, 36) = 9,916 P = 0,0033 F (1, 40) = 7,254 P = 0,0103 F (1, 35) = 2,316 P = 0,1370
Genotype F (1, 36) = 33,88 P < 0,0001 F (1, 40) = 34,27 P < 0,0001 F (1, 35) = 56,71 P < 0,0001
Treatment F (1, 36) = 28,40 P < 0,0001 F (1, 40) = 19,45 P < 0,0001 F (1, 35) = 2,316 P = 0,1370
GAD65   F (1, 39) = 6,545 P = 0,0145 F (1, 42) = 0,1534 P = 0,6973 F (1, 36) = 0,2613 P = 0,6123
  F (1, 39) = 13,71 P = 0,0007 F (1, 42) = 31,62 P < 0,0001 F (1, 36) = 39,19 P < 0,0001
  F (1, 39) = 6,511 P = 0,0148 F (1, 42) = 1,082 P = 0,3041 F (1, 36) = 0,2301 P = 0,6344
VGAT1   F (1, 37) = 3,352 P = 0,0752 F (1, 38) = 1,726 P = 0,1968 F (1, 35) = 5,556 P = 0,0241
  F (1, 37) = 26,76 P < 0,0001 F (1, 38) = 37,29 P < 0,0001 F (1, 35) = 8,755 P = 0,0055
  F (1, 37) = 2,844 P = 0,1002 F (1, 38) = 8,845 P = 0,0051 F (1, 35) = 5,364 P = 0,0265
PSD95   F (1, 38) = 35,74 P < 0,0001 F (1, 43) = 15,17 P = 0,0003   
  F (1, 38) = 31,22 P < 0,0001 F (1, 43) = 32,35 P < 0,0001   
  F (1, 38) = 60,35 P < 0,0001 F (1, 43) = 6,183 P = 0,0169   
GLUR2   F (1, 40) = 0,7223 P = 0,4005 F (1, 44) = 2,214 P = 0,1439 F (1, 37) = 6,726 P =  = 0,0135
  F (1, 40) = 13,28 P = 0,0008 F (1, 44) = 9,983 P = 0,0029 F (1, 37) = 8,465 P = 0,0061
  F (1, 40) = 16,26 P = 0,0002 F (1, 44) = 36,55 P < 0,0001 F (1, 37) = 7,370 P = 0,0100
NR2A   F (1, 39) = 3,725 P = 0,0609 F (1, 42) = 8,178 P = 0,0066 F (1, 36) = 20,05 P < 0,0001
  F (1, 39) = 11,09 P = 0,0019 F (1, 42) = 4,991 P = 0,0309 F (1, 36) = 0,0003 P = 0,9859
  F (1, 39) = 0,0944 P = 0,7602 F (1, 42) = 0,1399 P = 0,7103 F (1, 36) = 18,57 P = 0,0001
VGLUT1   F (1, 38) = 21,63 P < 0,0001 F (1, 42) = 0,2429 P = 0,6247 F (1, 35) = 4,167 P = 0,0488
  F (1, 38) = 38,92 P < 0,0001 F (1, 42) = 4,343 P = 0,0433 F (1, 35) = 0,02035 P = 0,8874
  F (1, 38) = 30,27 P < 0,0001 F (1, 42) = 3,706 P = 0,0610 F (1, 35) = 4,908 P = 0,0333
VGAT1/VGLUT1   F (1, 38) = 25,91 P < 0,0001 F (1, 42) = 5,230 P = 0,0273 F (1, 33) = 0,9883 P = 0,3274
  F (1, 38) = 1,337 P = 0,2549 F (1, 42) = 14,00 P = 0,0005 F (1, 33) = 7,328 P = 0,0107
  F (1, 38) = 30,40 P < 0,0001 F (1, 42) = 19,61 P < 0,0001 F (1, 33) = 0,2727 P = 0,6050