Figure 2 | Scientific Reports

Figure 2

From: Lifeact-TagGFP2 alters F-actin organization, cellular morphology and biophysical behaviour

Figure 2

Dose-response curves quantifying the effect of Lifeact expression in cell spread area (a), cell perimeter stellate factor (b), aspect ratio (c), f-actin amount (d), fibre thickness (d) and chirality of fibres (f). Values for >100 cells were pooled together to compute each individual data point. Data is presented as geometric mean (a,d), mean (b,e) or median (c,f) error bars indicate geometric standard deviation, standard deviation or Q1-Q3, accordingly. Background colours indicate the regimes where cells display no Lifeact-induced effect (yellow background), a dose-response trend (white background) and a saturation plateau (gray background), as identified from analyses of peak changes in variability in the neighbourhood of each point for each parameter plotted.

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