Figure 3 | Scientific Reports

Figure 3

From: Microarray assessment of N-glycan-specific IgE and IgG profiles associated with Schistosoma mansoni infection in rural and urban Uganda

Figure 3

Age-stratified prevalence of S. mansoni infection and median IgE and IgG reactivity to SWA, SEA and α-1,3-fucosylated and β-1,2-xylosylated N-glycans. (a,e) Rural and urban prevalence and intensity of S. mansoni infection, by age group. (b,f) Median IgG, IgG4 and IgE reactivity to SWA and SEA, by age group, among rural and urban participants, respectively. (c,g) Median IgE reactivity to the Man3GlcNAc2 core and to α3Fuc- and/or β2Xyl modified Man3GlcNAc2 core structures, by age group, among rural and urban participants, respectively. Plotted results are from all participants, irrespective of Sm infection status. (d,h) Median IgG reactivity to the Man3GlcNAc2 core and to α3Fuc- and/or β2Xyl-modified Man3GlcNAc2 core structures, by age group, among rural and urban participants, respectively. Plotted results are from all participants, irrespective of Sm infection status. CCA: S. mansoni infection determined by a positive urine circulating cathodic antigen (CCA) result; KK: S. mansoni infection determined by detection of eggs in a single stool sample by Kato-Katz (KK); epg: Eggs per gram of stool; SWA: Schistosoma adult worm antigen; SEA: Schistosoma egg antigen.

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