Figure 3 | Scientific Reports

Figure 3

From: The impact of proliferation-migration tradeoffs on phenotypic evolution in cancer

Figure 3

Joint evolution of migration and proliferation as influenced by three different tradeoff boundaries: open, convex, and concave. (A) The spatial layout and (B) the frequency of trait combinations is shown for a single representative simulation for each case, where the red points and line mark the average trait values every 5 days. The background colors correspond to the density of cell traits after reaching capacity; Brightly colored areas correspond to high densities, and the completely white area contains no cells. Replicate simulation runs are shown in Fig. S1 (top).

Back to article page