Table 2 CFT073 induced gene downregulation compared to unstimulated renal fibroblasts.

From: Human renal fibroblasts are strong immunomobilizers during a urinary tract infection mediated by uropathogenic Escherichia coli

Gene symble Fold change Description
KIT −24,3 Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
PTCH1 −13,1 Homo sapiens patched 1
TET1 −9,3 Homo sapiens tet methylcytosine dioxygenase 1
CEBPA-AS1 −8,6 Homo sapiens CEBPA antisense RNA 1
PLCB2 −8,2 Homo sapiens phospholipase C, beta 2
EEPD1 −7,7 Homo sapiens endonuclease/exonuclease/phosphatase family domain containing 1
CPEB1 −7,6 Homo sapiens cytoplasmic polyadenylation element binding protein 1
FIGNL2 −7,0 Homo sapiens fidgetin-like 2
GRASP −6,9 Homo sapiens GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
TOX −6,7 Homo sapiens thymocyte selection-associated high mobility group box
MKNK2 −6,6 Homo sapiens MAP kinase interacting serine/threonine kinase 2
STAM-AS1 −6,6 Homo sapiens STAM antisense RNA 1
SNHG22 −6,6 Homo sapiens small nucleolar RNA host gene 22
ADRA2A −6,3 Homo sapiens adrenoceptor alpha 2A
RCOR2 −6,2 Homo sapiens REST corepressor 2
CEBPA −6,1 Homo sapiens CCAAT/enhancer binding protein (C/EBP), alpha
SSTR1 −5,9 Homo sapiens somatostatin receptor 1
CSRNP3 −5,8 Homo sapiens cysteine-serine-rich nuclear protein 3
RGCC −5,8 Homo sapiens regulator of cell cycle
MEX3B −5,7 Homo sapiens mex-3 RNA binding family member B
THBD −5,7 Homo sapiens thrombomodulin
ZNF518A −5,6 zinc finger protein 518A
EPHB3 −5,6 Homo sapiens EPH receptor B3
GAS6-AS1 −5,6 Homo sapiens cDNA FLJ35543 fis, clone SPLEN2002957
E2F7 −5,5 Homo sapiens E2F transcription factor 7
KCNE3 −5,5 Homo sapiens potassium channel, voltage gated subfamily E regulatory beta subunit 3
CAMKK1 −5,5 Homo sapiens calcium/calmodulin-dependent protein kinase kinase 1, alpha
GAS1 −5,3 Homo sapiens growth arrest-specific 1
TRIM45 −5,3 Homo sapiens tripartite motif containing 45
SLC52A1 −5,3 Homo sapiens solute carrier family 52