Figure 9 | Scientific Reports

Figure 9

From: On-target and off-target effects of novel orthosteric and allosteric activators of GPR84

Figure 9

The effect of PSB-16671 in mouse bone marrow-derived neutrophils is not via GPR35. Interactions between eYFP-tagged forms of human GPR35a (a) or mouse GPR35 (b) and a luciferase-tagged form of β-arrestin 2 was assessed following co-transfection into HEK293 cells and the addition of the indicated concentrations of the GPR35 agonist lodoxamide, 2-HTP or PSB-16671. Results are taken from three independent experiments.

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