Figure 5 | Scientific Reports

Figure 5

From: Smart bone plates can monitor fracture healing

Figure 5

Histology sections for all bone plate model mice. Histology sections are stained and false-colored like in Fig. 2. Green = cartilage converting to bone. Black arrows point to sensors embedded in the fracture callus. Sample labels (upper right corner) are colored to match the graphs in Fig. 4I–K. (A–C) Histology sections for mice sacrificed at day 12. (D–F) Histology sections for mice sacrificed at day 26 with fracture calli composed almost entirely of new trabecular bone. (G–H) Histology sections of mice sacrificed at day 26 that experienced mixed healing. (I) Representative histology section of a control mouse, where the sensor is embedded in a small amount of fibrous tissue. (J–L) R2t is significantly correlated to % cartilage as well as to % trabecular bone. R2t also trends with % fibrous tissue. Individual markers are colored to match the corresponding samples in Fig. 4I–K.

Back to article page