Table 1 Secondary structural analyses of native TTR, dimer, and oligomer using the software DichroWeb.

From: Transthyretin Aggregation Pathway toward the Formation of Distinct Cytotoxic Oligomers

  α-helix (%) β-sheet (%) disordered (%) RMSD
Native (pdb: 1F41)) 5.5 48 46.5
WT Native 7 42 51 0.012
Dimer 3 34.5 62.5 0.023
Oligomer 6 38 57 0.022