Figure 1 | Scientific Reports

Figure 1

From: Potassium usnate, a water-soluble usnic acid salt, shows enhanced bioavailability and inhibits invasion and metastasis in colorectal cancer

Figure 1

Usnic acid showed in vitro anticancer activity in colorectal cancer cells. (A) Relative cell viability of HCT116, DLD1, SW480, HT29, SW620, Caco2, CT26, and COLO320 cells treated with usnic acid (UA). (B,C) Invasion assays in Caco2, HCT116, and CT26 cells treated with 5 μM UA (B), and quantification of invaded cell numbers in each group (C). (D) Quantitative analysis of metastasis score in isolated mouse liver tissues from orthotopic liver metastasis models (n = 4 each group). “10x” denote that UA was administered ten times within 2 weeks, while without indication denotes that of six times. Results are reported as the mean ± standard error of the mean.