Figure 5 | Scientific Reports

Figure 5

From: Visualising the dynamics of live pancreatic microtumours self-organised through cell-in-cell invasion

Figure 5

Membranous expression of α-tubulin in human PDAC specimens. (a,b) Histological analysis of human PDAC specimens. (a,b) Cell-in-cell structures and membranous α-tubulin expression in human PDAC specimens. HE staining and immunostaining for α-tubulin in a PanIN lesion from PDAC patient 1 (a). Normal pancreatic ducts and PanIN (upper panels), and invasive PDAC (lower panels) in PDAC Patient 2 (b). N: normal pancreatic ducts, M: malignant lesion in pancreatic ducts. HE staining and immunostaining for α-tubulin in invasive PDAC from PDAC patient 2 (c). Normal pancreatic ducts and PanIN (left panels), and invasive PDAC (right panels) in PDAC patient 3 (d). Invasive PDAC from PDAC patients 4, 5 and 6 (e). Arrow heads indicate cell-in-cell structures formed by live cells and arrows indicate cell-in-cell structures formed by dead cells.

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