Figure 6 | Scientific Reports

Figure 6

From: Histone H3K9 demethylase JMJD2B induces hepatic steatosis through upregulation of PPARγ2

Figure 6

Adenovirus-mediated JMJD2B overexpression promotes the expression of PPARγ2 and its steatosis target genes in mouse liver. C57BL/6 mice (8 weeks old) were injected with adenovirus Ad-GFP or Ad-JMJD2B. After injection, Ad-injected mice were fed a HFD for 2 weeks. (A) PPARγ2 expression was measured by qPCR. (B,C) The expression of PPARγ2 steatosis target genes was measured by qPCR. Data represent means ± SEM from 5 mice. *p < 0.05, **p < 0.01 vs. Ad-GFP-infected mice.

Back to article page