Figure 9 | Scientific Reports

Figure 9

From: Quantitative phase imaging unravels new insight into dynamics of mesenchymal and amoeboid cancer cell invasion

Figure 9

Amoeboid cell bleb measurements. Images of amoeboid cells embedded in 3D rat-tail collagen (1 mg/ml) acquired by CCHM were analysed to compute mean mass densities of cell bodies, pseudopodia and blebs in context of the observed amoeboid phenotypes. Overall, 10 cells and their pseudopodia and blebs were measured repeatedly with time interval between measurements long enough for cells to substantially changed their morphology. Cell body (n = 10), pseudopodium (n = 15), bleb (n = 88). Quantification results are expressed as box and whiskers (minimum to maximum). Statistical significance was determined by one-way ANOVA followed by Tukey’s post-hoc test.

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