Figure 4 | Scientific Reports

Figure 4

From: Quantitative phase imaging unravels new insight into dynamics of mesenchymal and amoeboid cancer cell invasion

Figure 4

Analysis of mean mass density in protrusions of migrating mesenchymal cells. Images of mesenchymal cells embedded in 3D bovine collagen (1 mg/ml) were analysed to compute mean mass densities in whole cells and individual protrusions. Quantification results are expressed as box and whiskers (minimum to maximum) of 10 different cells. Cells were measured two to five times with time interval between measurements long enough for cells to substantially changed their morphology. Cell body (n = 22), leading (n = 20), retracting (n = 16), side (n = 50). Statistical significance was determined by one-way ANOVA followed by Tukey’s post-hoc test.

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