Figure 1 | Scientific Reports

Figure 1

From: Quantitative phase imaging unravels new insight into dynamics of mesenchymal and amoeboid cancer cell invasion

Figure 1

Migration of a mesenchymal cell within collagen matrix. Cells were embedded in 3D bovine collagen (1 mg/ml) and migration was observed by CCHM. Representative images with indicated times are shown. It can be noticed that the cell follows a thicker fibre (indicated by an arrow) once it gets to contact with it. The thickness of fibres was measured using ImageJ Plot Profile tool. The thick fibre has an average value 0.66 µm. The average value of the thinner fibres that are surrounding the cell in any direction or are in contact with the cell, is 0.39 µm (median 0.37 µm; n = 30). For full sequence see Suppl. Video V1. Scale bar: 10 μm.

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