Figure 4 | Scientific Reports

Figure 4

From: Preventive treatment with liraglutide protects against development of glucose intolerance in a rat model of Wolfram syndrome

Figure 4

Serum insulin, C-peptide, and glucagon levels before and 30 minutes after glucose administration. (ad) Insulin levels after various time on liraglutide treatment, (e) C-peptide and (f) glucagon levels after 19 weeks on liraglutide treatment. The data were compared using repeated measures ANOVA followed by Tukey’s HSD tests; *p < 0.05, **p < 0.01, ***p < 0.001 compared to the baseline of the same animals; #p < 0.05, ##p < 0.01, ###p < 0.001 compared to WT animals of same treatment at the same timepoint; ¤p < 0.05, ¤¤¤p < 0.001 compared to saline treatment of the same GT at the same timepoint. The data are presented as the mean ± SEM, n = 12–15.

Back to article page