Table 1 Baseline and cumulative clinical characteristics of cSLE and aSLE.

From: Genetic variants in systemic lupus erythematosus susceptibility loci, XKR6 and GLT1D1 are associated with childhood-onset SLE in a Korean cohort

  cSLE aSLE p
Age of SLE onset, year, mean ± SD 12.5 ± 2.5 29.0 ± 9.4 <0.001
Sex, female, N (%) 78 (81.3) 653 (95.3) <0.001
Disease duration, year, mean ± SD 3.3 ± 3.6 2.9 ± 3.4 0.248
Follow-up duration, year, mean ± SD 10.7 ± 4.7 10.5 ± 5.3 0.770
range 1.7–20.9 0.2–30.3  
At the time of enrollment
  The number of ACR criteria, mean ± SD 5.3 ± 1.4 5.1 ± 1.4 0.210
  SLEDAI, mean ± SD 5.6 ± 4.6 5.5 ± 4.4 0.897
  SDI > 1, N (%) 19 (19.8) 204 (29.8) 0.42
At the time of last follow-up
  The number of ACR criteria, mean ± SD 6.1 ± 1.6 5.6 ± 1.4 0.001
  AMS, mean ± SD 4.9 ± 2.6 4.2 ± 2.6 0.017
  SDI > 1, N (%) 38 (39.6) 325 (47.7) 0.148
  1. cSLE, childhood-onset systemic lupus erythematosus; aSLE, adult-onset systemic lupus erythematosus; SD, standard deviation; ACR, American College of Rheumatology; SLEDAI, the SLE disease activity index; SDI, the Systemic Lupus International Collaborating Clinics/ACR SLE Damage Index; AMS, the Adjusted Mean SLEDAI-2K.