Figure 10 | Scientific Reports

Figure 10

From: Protein-bound NAD(P)H Lifetime is Sensitive to Multiple Fates of Glucose Carbon

Figure 10

NAD(P)H \({\tau }_{2}\) is sensitive to cellular fuel source. (a–f) Mean and standard deviations of NAD(P)H \({\tau }_{2}\) (a), optical redox ratio (b), NAD(P)H intensity (c), NAD(P)H \({\alpha }_{1}\) (d), NAD(P)H \({\tau }_{1}\) (e), and NAD(P)H \({\tau }_{m}\) (f) of fuel-starved MCF10A cells before and after addition of 10 mM sodium pyruvate. (g–l) Mean and standard deviations of NAD(P)H \({\tau }_{2}\) (g), optical redox ratio (h), NAD(P)H intensity (i), NAD(P)H \({\alpha }_{1}\) (j), NAD(P)H \({\tau }_{1}\) (k), and NAD(P)H \({\tau }_{m}\) (l) of fuel-starved MCF10A cells before and after addition of 10 mM sodium lactate. ns = p > 0.05 vs. control. *p < 0.05 vs. control. n = 3 experiments each.

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