Metagenome isolation and sequencing library construction. (A) A schematic diagram of the bacterial metagenome isolation. The large dinoflagellate genome size and DNA content per cell is represented in the top and the enrichment of the bacterial metagenome by the lysis of microalgae is represented on the bottom. (B) PCR amplification results from the 16S rRNA and 18S rRNA gene amplification from the isolated bacterial metagenome. (C) Schematic diagram showing the different method characteristics and the analytic pipeline for 16S rRNA metagenome analysis using Illumina and MinION sequencing platforms.