Table 6 List of downregulated genes of UA159 in the presence of S-PRG eluate, which were observed in either MT8148 or UA159 under three different conditions using DNA microarray analysis.

From: Inhibitory effect of surface pre-reacted glass-ionomer (S-PRG) eluate against adhesion and colonization by Streptococcus mutans

Gene Accession number S-PRG 0% S-PRG 6.3% S-PRG12.5% S-PRG 25.0%
Signal Signal Log2* Change# Signal Log2* Change# Signal Log2* Change#
bcc 721410.1 5980.6 1943.9 −1.62 0.325 1876.8 −1.67 0.314 1108.3 −2.43 0.185
celR 721935.1 11936 1137.1 −3.4 0.095 366.9 −5.02 0.031 38.4 −8.3 0.003
cilA 721415.1 5421.4 1804.4 −1.59 0.332 1879 −1.53 0.347 726.1 −2.9 0.134
cilB 721414.1 3708.8 1459.6 −1.34 0.394 1488.8 −1.32 0.402 712.4 −2.38 0.192
cilG 721413.1 4245.9 1734 −1.29 0.408 1999.6 −1.09 0.471 1059.9 −2 0.249
citC 721405.1 1927.9 218.7 −3.15 0.113 121.6 −3.99 0.063 164.4 −3.55 0.085
citG 721406.1 1543.6 282.1 −2.45 0.183 138.2 −3.48 0.089 183.1 −3.1 0.117
citG2 721416.1 5644.4 1906.9 −1.56 0.338 1774.5 −1.67 0.314 694.5 −3.02 0.123
coaA 721513.1 126.2 39.1 −1.69 0.31 49.8 −1.34 0.395 54.6 −1.21 0.433
comEA 721053.1 135.8 67.9 −1 0.5 29.2 −2.22 0.215 29.5 −2.21 0.217
comYA 722285.1 231.2 37.6 −2.65 0.159 17.9 −3.74 0.075 28.8 −3.02 0.124
comYB 722284.1 606.2 90 −2.76 0.148 42 −3.87 0.069 69 −3.14 0.113
comYC 722283.1 903.7 109.7 −3.05 0.121 45.5 −4.34 0.049 102.2 −3.14 0.113
comYD 722282.1 750.9 89.6 −3.13 0.114 38 −4.34 0.05 70.7 −3.43 0.093
galR 721293.1 998.6 467 −1.1 0.468 222.2 −2.17 0.222 396.7 −1.33 0.397
grpE 720560.1 40392.6 24381 −0.72 0.603 15498.9 −1.38 0.384 23261.7 −0.8 0.576
hsdM 721299.1 236.4 230.2 −0.04 0.974 233.2 −0.02 0.986 693.4 1.55 2.933
lacA 721844.1 1232.9 487.2 −1.34 0.395 115.2 −3.42 0.093 34 −5.19 0.027
lacB 721843.1 3958.7 974.1 −2.02 0.246 263.3 −3.91 0.066 59.5 −6.09 0.015
lacC 721842.1 2894.5 707.6 −2.03 0.245 203.3 −3.83 0.07 44.2 −6.07 0.015
lacD 721841.1 2529.6 976.9 −1.37 0.386 173.4 −3.88 0.068 25.2 −6.65 0.01
lacD2 720591.1 1990.2 422.6 −2.24 0.212 162.4 −3.61 0.082 39.2 −5.67 0.02
lacE 721839.1 4352.6 1160.3 −1.91 0.267 303.3 −3.85 0.07 71.2 −5.93 0.016
lacF 721840.1 3438.8 936 −1.88 0.272 227.8 −3.92 0.066 38.3 −6.54 0.011
lacG 721838.1 30256.7 6224.5 −2.28 0.206 1223.1 −4.63 0.04 270.5 −6.81 0.009
lacX 721837.1 2139.1 804.4 −1.41 0.376 251.6 −3.09 0.118 84.2 −4.67 0.039
lytR 721011.1 1717.4 772.8 −1.15 0.45 841.5 −1.03 0.49 419.1 −2.04 0.244
oadB 721411.1 11315.4 4350.1 −1.38 0.384 4811.2 −1.23 0.425 2660.8 −2.09 0.235
pflC 720930.1 1164.2 478.1 −1.28 0.411 391.9 −1.57 0.337 544.7 −1.1 0.468
ptcA 721934.1 7508.6 633.3 −3.57 0.084 207.5 −5.19 0.027 17.7 −8.74 0.002
ptcB 721936.1 615.6 239.6 −1.37 0.388 103.5 −2.58 0.167 21.7 −4.84 0.035
ptcC 721932.1 2921 366.2 −3 0.125 124.6 −4.56 0.043 38.5 −6.25 0.013
pycB 721417.1 22423.4 5598.4 −2 0.25 4989.7 −2.17 0.223 2210.2 −3.34 0.099
rgpG 720710.1 1621.9 1575.5 −0.04 0.971 1983.1 0.29 1.223 4685.6 1.53 2.889
scnE 722129.1 324.3 412.9 0.35 1.273 291.9 −0.15 0.9 284 −0.19 0.876
spaP 721042.1 3168.9 3842.9 0.28 1.212 2127.1 −0.58 0.671 2296.4 −0.47 0.724
ssb2 722266.1 769.7 369.5 −1.06 0.48 271.3 −1.51 0.352 308.6 −1.32 0.401
trk 721902.1 14957.3 11522.8 −0.38 0.77 10018.8 −0.58 0.67 3609 −2.05 0.241
trkB 721901.1 10436.8 7856.4 −0.41 0.753 7320 −0.51 0.701 2494.6 −2.06 0.239
wapA 721382.1 3891.4 2323.7 −0.74 0.597 1931.4 −1.01 0.496 568.7 −2.78 0.146
  1. *Log2 means Log2 ratio. #Change means Fold change. The Log2 ratio and Fold change were calculated by signal with each concentration of S-PRG eluate/signal without S-PRG eluate.