Correction to: Scientific Reports https://doi.org/10.1038/s41598-017-02190-5, published online 26 May 2017
This Article contains typographical errors in the Results section.
“No mesenchymal changes and migratory cells was observed when TGF-β1 was treated first and then treated with TNF-α. The similar results were shown in immunostaining with α-SMA and also in quantification of α-SMA positive colonies.”
should read:
“No mesenchymal changes and migratory cells was observed when TGF-β1 was treated first and then treated with TNF-α (Fig. 3E). The similar results were shown in immunostaining with α-SMA (Fig. 3F)and also in quantification of α-SMA positive colonies (Fig. 3G).”
“When TNF-α and TGF-β1 treated cIEOs were immunostained for α-SMA and Ki67, almost all the mesenchymal changed colonies exhibited mesenchymal and proliferation markers.”
should read:
“When TNF-α and TGF-β1 treated cIEOs were immunostained for α-SMA and Ki67, almost all the mesenchymal changed colonies exhibited mesenchymal and proliferation markers (Fig. 4B).”
Additionally, this Article contains errors in Figure 6, where the panels are incorrectly labeled. As a result, in the Figure legend,
“(B) The percentage of α-SMA positive colonies was determined. Data were presented as the mean ± SEM; n = 4 samples per bar, **p < 0.01. (C) The expression of α-SMA and Ki67 was examined in TGF-β1 treated IEOs with or without inhibitors. Bars, 50 μm.”
should read:
“(B) The expression of α-SMA and Ki67 was examined in TGF-β1 treated IEOs with or without inhibitors. Bars, 50 μm. (C) The percentage of α-SMA positive colonies was determined. Data were presented as the mean ± SEM; n = 4 samples per bar, **p < 0.01.”
The correct Figure 6 appears below as Figure 1.
TNF-α promotes mesenchymal phenotypic changes in TGF-β1 treated IEOs by regulating gene expression associated with EMT. (A) Representative images of the IEOs following TNF-α, TGF-β treatment with or without inhibitors. Bars, 100 μm. (B) The expression of α-SMA and Ki67 was examined in TGF-β1 treated IEOs with or without inhibitors. Bars, 50 μm. (C) The percentage of α-SMA positive colonies was determined. Data were presented as the mean ± SEM; n = 4 samples per bar, **p < 0.01. (D) Relative mRNA expression for EMT-related transcription factors was quantified after TNF-α treatment in IEOs. (E) Relative mRNA expression for EMT effector genes was quantified after TNF-α treatment in IEOs. Data are presented as the mean ± SEM; n = 3 samples per bar, *p < 0.05, control versus TNF-α or inhibitors; #p < 0.05, TNF-α versus inhibitors.
Author information
Authors and Affiliations
Corresponding authors
Additional information
The original article can be found online at https://doi.org/10.1038/s41598-017-02190-5.
The original article can be found online at https://doi.org/10.1038/s41598-017-02190-5.
Rights and permissions
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
About this article
Cite this article
Hahn, S., Nam, MO., Noh, J.H. et al. Author Correction: Organoid-based epithelial to mesenchymal transition (OEMT) model: from an intestinal fibrosis perspective. Sci Rep 8, 4303 (2018). https://doi.org/10.1038/s41598-018-22624-y
Published:
DOI: https://doi.org/10.1038/s41598-018-22624-y
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
