Table 2 IC50 values of hit compounds against human norovirus Sydney 2012 RdRp activities.

From: In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase

Compound Name Structure Molecular weight IC50 values [µM]A (95% confidence interval)
11 506.56 5.0 (2.4–10.6)
13 456.47 15.0 (7.4–27.4)
54 485.52 5.6 (4.1–7.6)
42a 404.45 27.4 (8.3–81.4)
42b 462.48 NDB
  1. AThe mean values of triplicate datasets are shown from at least two independent experiments. BCompound too insoluble to attain an accurate IC50 measurement.