Figure 2 | Scientific Reports

Figure 2

From: Localization of lipopolysaccharide from Escherichia Coli into human atherosclerotic plaque

Figure 2

Morphological changes of activated macrophages. Immunostaining for LPS (A) and TLR4 (B) in carotid plaque revealed that in the area where the immunoreactivity for antibodies against LPS from Escherichia Coli (EC) (A) or for antibodies against TLR4 (B) was higher, macrophages CD68 positive showed signs of activation (red star). They appeared bigger compared to non-activated macrophages (arrow), which, conversely, were detected in the area with a less reactivity to LPS and TLR4 and disclosed typical round shape.

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